So, like we did for hormones and receptors, let’s review what cancer is, briefly.
Then we’ll look at estrogenic impact.
All types of cancers—lung cancer, breast cancer, etc.—arise because DNA (or
epiDNA but let’s not go there yet) ends up with a critical mutation. We’re not
talking about just any mutation, we’re talking about something “critical”. To
give rise to cancer, the mutation must be on a DNA gene involved in cell growth,
cell multiplication, or cell spreading (scientists call these actions “proliferations,
propagations, and metastases”).
And it generally isn’t just one mutation. A study of 12 tumor types found that
an average of 2-6 mutations in “critical” genes gave rise to those tumors. That’s
2-6 mutations in genes involved in cell growth, multiplication, and spreading.27
In your body, many of your more “exposed” cells—like your skin cells, blood
vessel cells, or intestine cells—acquire mutations all the time.
We all have over 3 billion base pairs of DNA, so it still generally takes a long
time to “hit” one of our important genes involved in cell growth, proliferation,
and propagation. Even exposed cells take a long time to acquire such mutations.
In fact, colon cancer requires—on average—over 11,000 mutations in the DNA
before a random “hit” is made in a gene involved in cell growth, multiplication,
and spreading that leads to cancer.28
The key word here is “random”. In other words, 11,000 random mutations
give rise to mutations in “critical” DNA areas purely by chance.
So, the deeper point I’m making is that cancer is a numbers game. You
“increase your odds” for cancer by eating and drinking estrogenics. Like a
“devil’s lottery” where lottery tickets are DNA mutations.
And after you get those mutations, the messed-up cells, the cancerous cells,
still need to survive. You may remember how I placed emphasis at the beginning
of the chapter on the relationship between the immune system and cancer? Well,
if your immune system detects a strange cancer, it can beneficially chew it up or
eat that cell and rid your body of it. This is why over a quarter million studies
have been done on “immune system + cancer”. It’s a hotbed of research.
Because of this relationship between our innate immunity and cancer,
chemicals that cause immune system damage might be predicted to also cause
cancer.

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